Upon our readers demand, this month we've reached out to Cosmedique, the manufacturer of the All-In-One Ultra-Concentrated Skin Rejuvenation Treatment, to determine the difference between the ingredients proven by studies and clinical trials and ingredients presumed to be beneficial.

So many products are created to smooth wrinkles and make age spots disappear, but how do you know which ones will actually deliver what they promise? We talked to experts to get the truth—and science—behind the key age-fighting ingredients.

What about the skincare products on your bathroom counter? Do they have proof they do what they say they do?

Maintaining your skincare regime using right product with clinically proven ingredients can preserve your young appearance long term, where their cheaper alternatives with presumed to be effective ingredients, may at their best work as a regular moisturizer. Choose wisely because there is no coming back. Once you commit those months or years to maintain your younger looking face and use something ineffective you may be left with very few options to recover from it.

Accumulation of “long” collagen fibers makes part of the skin looser and stiffer, and as a consequence, a big fold of skin appears. When a “long” collagen is broken in a compressed state, it may be replaced by a “short” collagen fiber. The “shorter” collagen fibers will restrict the extension of “longer” fibers, and make the “long” fibers in a folding state permanently. A small fold, namely a permanent wrinkle, then appears.


Often referred to as “facelift in a tube.” While many ingredients can reduce the appearance of wrinkles, it’s DMAE that can actually lift sagging skin. When synthesized in a lab and blended into skin care products, DMAE relaxes fine lines and wrinkles and assists in firming sagging and aging skin, resulting in an overall more tightened, toned and youthful appearance. DMAE has also been shown to have anti-inflammatory effects that reduce symptoms of sun damage and improve skin firmness and muscle tone, too


An antioxidant and a cell-communicator, this vitamin derivative increases collagen production in your skin. It also enhances glycosaminoglycan content, producing firmer skin with superior texture and reinforced barrier function to keep skin healthy and strong.

Caviar Extract

Caviar has a cell format similar to human skin and is known to provide unparalleled nourishment and mineralization of the skin. The caviar anti aging extract used in Caviar of Switzerland products such as "Cosmedique Ultra-Concentrated Skin Rejuvenation Treatment", comes from a special farm in France and is then sent to a Swiss laboratory to be formulated for cosmetic use. This is the finest caviar used in aesthetics. The caviar extracted from the water after the natural hatching process is completed, without harming animals in any way.

Hyaluronic Acid

A natural structural component of skin that holds moisture better than any synthesized polymer. It helps rejuvenate the skin's barrier with moisturizing, and adds antioxidant defense against free radicals; also reduces inflammation.


The main ingredient of your skin's intercellular matrix, ceramides form the "glue" that holds skin cells together, preserving appearance and defending against aging. When the skin's outer barrier is damaged from irritation or too much sun, ceramide content is diminished, leaving your skin exposed. Replenishing your skin's ceramides protects and restores youthful vitality.

Vitamin C

Possibly the most beneficial vitamin you can apply to your skin. Anti-aging functions include increased collagen production, reduced skin discoloration, strengthened barrier response, enhanced natural repair processes, and reduced inflammation. This vitamin is essential in helping your skin withstand overexposure to UV light.

Where you can find it all: Above are the most important and the most effective ingredients - according to multiple studies. You can find all of them in this one, paraben-free and silicone-free product: "Cosmedique Ultra-Concentrated Skin Rejuvenation Treatment"

Limited-Time Exclusive Offer

As a response to a massive amount of inquiries from our readers. We’ve decided to reach out directly to Cosmedique. They've agreed to provide our readers with a 30-day trial to experience the full efficacy of their product before deciding to purchase it.

(Worldwide shipping is available)